Helen Lamb
- Grad Group: Biochemistry, Molecular, Cellular and Developmental Biology
- Major Professor: Lesilee Rose
- Lab Phone:
- Email Helen
Degrees
- BA - Pomona College - Biology - 2015
- PhD - University of California, Davis - BMCDB - 2023
Fellowships
MCB T32 Training Program
2017
- 2019
Research Interest Summary
Embryonic cell biology: establishment and maintenance of cell polarity during asymmetric division; orientation of the mitotic spindle during asymmetric division.
Research Interests
Embryonic cell biology: establishment and maintenance of cell polarity during asymmetric division; orientation of the mitotic spindle during asymmetric division.
Publications
- Lamb H., Liro M.J., Myles K.M., Anderson H., Rose L.S. (2024). The Rac1 homolog CED-10 is a component of the MES-1/SRC-1 pathway for mitotic spindle positioning in the C. elegans EMS blastomere. bioRxiv. doi: https://doi.org/10.1101/2024.04.04.588162
- Price K.L., Lamb H., Alvarado J., Rose L.S. (2022). The DEPDC1 protein LET-99 is required for cortical stability and antagonizes branched actin formation to promote robust cytokinesis. bioRxiv. https://doi.org/10.1101/2022.09.07.506988
- Konopelski Snavely S.E., Susman M.W., Kunz R.C., Tan, J., Srinivasan S., Cohen M.D., Okada K., Lamb H., Choi S.S., Karuna E.P., Scales M.K., Gygi S.P., Greenberg M.E., Ho H.H. (2021). Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling. PNAS 118(25): e2104944118. https://doi.org/10.1073/pnas.2104944118
- González D.P., Lamb H.V., Partida D., Wilson Z.T., Harrison M.-C., Prieto J.A., Moresco J.J., Diedrich J.K., Yates J.R. III, Olson S.K. (2018). CBD-1 scaffolds two independent complexes required for eggshell vitelline layer formation and egg activation in C. elegans. Developmental Biology 442(2): 288-300. https://doi.org/10.1016/j.ydbio.2018.08.005